Endospore Enumeration With BactoBox

Explore the capabilities of BactoBox for precise, rapid enumeration of bacterial spores.  We have developed an application note that details how to configure BactoBox beyond its default settings for counting intact cells to rapidly enumerate endospores, including correlation data with CFUs for Bacillus spore counting. As industries increasingly utilize spores in biotherapeutic and probiotic applications, the need for efficient and reliable enumeration techniques becomes paramount. BactoBox offers a robust, label-free solution, ideal for real-time process control and accurate counting of spore populations.

Technical insights from application note

  • Distinct Electrical Properties: BactoBox differentiates between vegetative cells and spores based on their unique electrical impedance signatures. Spores, characterized by their low conductivity and small signal amplitudes, are easily distinguishable from other cell types.
  • Real-Time Monitoring Capabilities: The application note details how BactoBox tracks sporulation processes in real-time, providing immediate feedback that is essential for optimizing biotechnological applications.
  • Comparison with Traditional Methods: The application note addresses the limitations of traditional spore enumeration methods, such as plate counts and fluorescence flow cytometry, highlighting BactoBox's ability to deliver faster and more reliable results without the need for extensive sample preparation or staining.

Highlights of using using BactoBox for endospore enumeration

  • Efficient and Accurate: With its non-invasive and label-free approach, BactoBox reduces the time and cost associated with spore enumeration while maintaining high accuracy and precision.
  • Operator Independent: Designed for ease of use, BactoBox can be operated with minimal training, reducing the potential for human error and the variability seen in traditional methods.
  • Versatile Applications: Ideal for a variety of settings, from pharmaceutical manufacturing to agricultural biotechnology, where rapid and precise microbial analysis is crucial.

Download the full application note

Delve deeper into the advanced features and functionalities of BactoBox for spore enumeration. Download the full application note here to learn about its impact on streamlining spore counting in diverse applications.

Enumerate Bacteria with BactoBox®

Enumerate Bacteria with BactoBox®

Enumerate Bacteria with BactoBox®

Please submit your contact and application details using the form below. A specialist from our team will contact you within one business day to discuss the technical compatibility of BactoBox® with your needs and outline potential trial opportunities. Alternatively, reach out directly to our CEO, Gustav.

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Gustav Skands

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Learn More or Request a Trial

Learn More or Request a Trial