Unlock The Full Potential of Your Fermentation Process

Unlock The Full Potential of Your Fermentation Process

Unlock The Full Potential of Your Fermentation Process

Direct live/dead bacterial cell counts in minutes

Direct live/dead bacterial cell counts in minutes

Direct live/dead bacterial cell counts in minutes

Case study: Optimize your upstream process development with unique data insights

Case Study: Optimize your upstream process development with unique data insights

Case study: Optimize your upstream process development with unique data insights

Are you reaching peak cell concentration 3x faster than your OD600 measurements indicate?

Are you reaching peak cell concentration 3x faster than your OD600 measurements indicate?

Are you reaching peak cell concentration 3x faster than your OD600 measurements indicate?

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Explore the unique insights BactoBox offers for your fermentation processes. In one case study, while the OD600 reading continued to rise until approximately 23.1 hours, BactoBox revealed that cell growth had actually plateaued after just 7.7 hours. This demonstrates that peak biomass is reached three times faster than traditional OD600 measurements indicate.

The advantages of direct cell counting become even more significant as the complexity of the fermentation process increases, such when endotoxin production affect viability. Many processes significantly alter the morphological characteristics of cells, impacting optical density readings and complicating rapid process development. Let BactoBox simplify and accelerate your bioprocessing workflows.

Explore the unique insights BactoBox offers for your fermentation processes. In one case study, while the OD600 reading continued to rise until approximately 23.1 hours, BactoBox revealed that cell growth had actually plateaued after just 7.7 hours. This demonstrates that peak biomass can be reached three times faster than traditional OD600 measurements indicate.

The advantages of direct cell counting become even more significant as the complexity of the fermentation process increases, such as with IPTG induction. These processes can significantly alter the morphological characteristics of cells, impacting OD600 readings and complicating rapid process development. Let BactoBox simplify and accelerate your bioprocessing workflows.

Easy workflow

Easy workflow

Easy workflow

Precise counts by pressing a button

Precise counts by pressing a button

Precise counts by pressing a button

BactoBox® offers an easy-to-use solution for performing bacteria enumeration in 2 minutes.

With its user-friendly interface, minimal training is required to achieve highly precise total bacteria counts in minutes.

Enjoy enhanced precision and accuracy with BactoBox®.

BactoBox® offers an easy-to-use solution for performing bacteria enumeration in 2 minutes.

With its user-friendly interface, minimal training is required to achieve highly precise total bacteria counts in minutes.

Enjoy enhanced precision and accuracy with BactoBox®.

BactoBox® offers an easy-to-use solution for performing bacteria enumeration in 2 minutes.

With its user-friendly interface, minimal training is required to achieve highly precise total bacteria counts in minutes.

Enjoy enhanced precision and accuracy with BactoBox®.

Implement next-gen analytical technology in your work

Implement next-gen analytical technology in your work

Elevate microbial fermentations to new heights

Elevate E. coli fermentations to new heights

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Save cost in process development

By providing precise, rapid bacterial counts, BactoBox allows you to optimize your fermentation, effectively reducing time and resource waste. The immediate insight into cell viability and density ensures that you can swiftly adjust parameters to maximize yield and quality.

Save cost in process development

By providing precise, real-time bacterial counts, BactoBox allows you to optimize your fermentation, effectively reducing time and resource waste. The immediate insight into cell viability and density ensures that you can swiftly adjust parameters to maximize yield and quality.

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Achieve profitability in your operations

BactoBox equips you with the insights needed to transition from a log-based science into an exact science with high repeatability. The results accurately guide you when exploring innovative approaches to optimization. BactoBox is an indispensable process analytical technology.

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Advance your fermentation

Abandon slow and cumbersome methods like dry cell weight, CFUs, wet cell weight, and other cell concentration proxies that are inaccurate and outdated. Track bacterial growth with precision, and count viable cells.

Learn exactly how BactoBox can help you in your work - reach out to us!

Reach out to learn more or get a trial in your lab

Reach out to learn more or get a trial in your lab


    Achieve your process development goals faster

    Achieve your process development goals faster

    Achieve your process development goals faster

    Correlate key fermentation metrics to live/dead cell counts almost instantly

    Correlate key fermentation metrics to live/dead cell counts almost instantly

    Correlate key fermentation metrics to live/dead cell counts almost instantly

    Bacterial Fermentation

    BactoBox serves as a pivotal instrument in the correlative analysis of essential fermentation metrics. Its precise live/dead cell counts are critical for interpreting and optimizing fermentation processes.

    • Correlate cell counts with oxygen transfer and uptake rates to refine your strategies for maintaining aerobic conditions to ensure optimal growth.
    • Utilize accurate bacterial enumeration to optimize inducer addition and maximize recombinant protein yields. Use the live/dead data to understand the adverse effects on your bacterial cells.
    • Use BactoBox data to determine when cells die, and employ amplitude data to discern changes in cell morphology during fermentation.

    Finally, a result expressed as intact cells/mL is directly transferable between labs and production facilities.